Product | Mechanism | Ownership | Indication | Preclinical | Clinical Stage Phase 1/2 |
---|---|---|---|---|---|
Tuspetinib* | Myeloid Kinase | Aptose WW | AML |
complete
AML
Preclinical Phase complete
|
in progress
Clinical Stage Phase 1/2 Phase in progress
|
Luxeptinib** | Lymphoid Kinase | Aptose: WW Crystal Genomics: Korea |
CLL & NHL |
complete
CLL & NHL
Preclinical Phase complete
|
in progress
Clinical Stage Phase 1/2 Phase in progress
|
Luxeptinib** | Myeloid Kinase | Aptose: WW Crystal Genomics: Korea |
AML & MDS |
complete
AML & MDS
Preclinical Phase complete
|
in progress
Clinical Stage Phase 1/2 Phase in progress
|
APTO-253 | MYC, KLF4 | Aptose: WW | AML & MDS |
complete
AML & MDS
Preclinical Phase complete
|
in progress
Clinical Stage Phase 1/2 Phase in progress
|
APL-581 | BRD4/JAK | Aptose and Ohm | Hematologic Cancers |
in progress
Hematologic Cancers
Preclinical Phase in progress
|
not started
Clinical Stage Phase 1/2 Phase not started
|
*formerly HM43239
**formerly CG-806
Luxeptinib is being developed for the treatment of patients with certain B-cell malignancies, including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and certain non-Hodgkin’s lymphomas (NHL) who are resistant or intolerant to conventional treatments.
View CandidateLuxeptinib is also being developed for the treatment of patients with relapsed or refractory acute myeloid leukemia (AML), including the emerging populations resistant to approved targeted therapies.
View CandidateTuspetinib (HM43239) is being developed for the treatment of patients with relapsed or refractory acute myeloid leukemia (AML).
View CandidateOur online library includes numerous publications, including presentations, posters, and other media that provide additional information on preclinical and clinical studies of our drug candidates.
View Posters & Presentations