About

A Pipeline to Change Conventional Anti-Cancer Therapies

A Pipeline to Change Conventional Anti-Cancer Therapies

At Aptose Biosciences, we are building a pipeline of novel and targeted oncology therapies with the potential to serve specific populations of cancer patients.

Our pipeline includes products designed to provide single agent efficacy and to enhance the efficacy of conventional anti-cancer therapies through simultaneous targeting of key drivers of disease in cancer cells without overlapping toxicities and thus preserving the quality of life in cancer patients.

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Clinical Trials

We have two clinical-stage investigational products for hematologic malignancies.

Clinical Trials for Aptose Biosciences

Aptose Biosciences has two clinical-stage investigational products for hematologic malignancies: tuspetinib, an oral, potent myeloid kinase inhibitor, and luxeptinib, an oral, dual lymphoid and myeloid kinase inhibitor.

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Tuspetinib
Tuspetinib

A Phase 1/2 Study of Tuspetinib (HM43239)  in AML

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Phase 1 a/b Study of Luxeptinib (CG-806) in CLL & NHL
Phase 1 a/b Study of Luxeptinib (CG-806) in CLL & NHL

Luxeptinib (CG-806), an oral, mutation-agnostic FLT3/BTK inhibitor, is in a Phase 1a/b study in patients with relapsed or refractory B-cell malignancies, including chronic lymphocytic leukemia (CLL) and non-Hodgkin’s lymphoma (NHL).

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Phase 1 a/b Study of Luxeptinib (CG-806) in AML.
Phase 1 a/b Study of Luxeptinib (CG-806) in AML.

Luxeptinib (CG-806), an oral, mutation-agnostic FLT3/BTK inhibitor, is in a Phase 1a/b study in patients with relapsed or refractory acute myeloid leukemia (AML).

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Our Leadership Team

Our Leadership Team

Our leadership team is comprised of distinguished individuals who possess an actionable blend of academic and industry experience, having served in numerous leadership roles throughout their careers.