About

A Pipeline to Change Conventional Anti-Cancer Therapies

A Pipeline to Change Conventional Anti-Cancer Therapies

At Aptose Biosciences, we are building a pipeline of novel and targeted oncology therapies with the potential to serve specific populations of cancer patients.

Our pipeline includes products designed to provide single agent efficacy and to enhance the efficacy of conventional anti-cancer therapies through simultaneous targeting of key drivers of disease in cancer cells without overlapping toxicities and thus preserving the quality of life in cancer patients.

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Clinical Trials

We have two clinical-stage investigational products for hematologic malignancies.

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Phase 1 a/b Clinical Study of CG-806
Phase 1 a/b Clinical Study of CG-806

CG-806, an oral, first-in-class pan-FLT3/pan-BTK inhibitor, is in a Phase 1 trial in patients with relapsed or refractory B cell malignancies, including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL) and non-Hodgkin lymphoma (NHL), who have failed or are intolerant to standard therapies.

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Phase 1b Clinical Study of APTO-253
Phase 1b Clinical Study of APTO-253

APTO-253, the only clinical-stage agent that directly targets the MYC oncogene and inhibits its expression, is in a Phase 1b clinical trial for the treatment of patients with relapsed or refractory blood cancers, including AML and high-risk MDS.

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Our Leadership Team

Our Leadership Team

Our leadership team is comprised of distinguished individuals who possess an actionable blend of academic and industry experience, having served in numerous leadership roles throughout their careers.