Clinical Trials
We have two clinical-stage investigational products for hematologic malignancies.
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A Pipeline to Change Conventional Anti-Cancer Therapies
At Aptose Biosciences, we are building a pipeline of novel and targeted oncology therapies with the potential to serve specific populations of cancer patients.
Our pipeline includes products designed to provide single agent efficacy and to enhance the efficacy of conventional anti-cancer therapies through simultaneous targeting of key drivers of disease in cancer cells without overlapping toxicities and thus preserving the quality of life in cancer patients.
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Phase 1 Study of CG-806 in CLL & NHL
Phase 1 Study of CG-806 in CLL & NHL
CG-806, an oral, mutation-agnostic FLT3/BTK inhibitor, is in a Phase 1 study in patients with relapsed or refractory B-cell malignancies, including chronic lymphocytic leukemia (CLL) and non-Hodgkin’s lymphoma (NHL).
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Phase 1a/b Study of CG-806 in AML
Phase 1a/b Study of CG-806 in AML
CG-806, an oral, mutation-agnostic FLT3/BTK inhibitor, is in a Phase 1a/b study in patients with relapsed or refractory acute myeloid leukemia (AML).
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Phase 1b Study of APTO-253 in AML & MDS
Phase 1b Study of APTO-253 in AML & MDS
APTO-253, the only clinical-stage agent that directly targets the MYC oncogene and inhibits its expression, is in a Phase 1b clinical trial for the treatment of patients with relapsed or refractory blood cancers, including AML and high-risk MDS.
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Our Leadership Team
Our leadership team is comprised of distinguished individuals who possess an actionable blend of academic and industry experience, having served in numerous leadership roles throughout their careers.