HM43239 for AML

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Trial Summary


A Phase 1/2 Open Label, Multicenter, Dose Escalation and Expansion Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HM43239 in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)


Acute Myeloid Leukemia

Actual Start Date

March 11, 2019

Estimated Primary Completion Date

January 2023

Detailed Info

Brief Summary

This is a Phase 1/2, open-label, multi-center study to assess the efficacy, safety,

tolerability, pharmacokinetics, including recommended phase 2 dose (RP2D) of HM43239

monotherapy in subjects with relapsed or treatment-refractory acute myeloid leukemia (AML).

Study Phase

Phase 1/Phase 2

Estimated Enrollment


Estimated Primary Completion Date

January 2023

Study Type



  • Drug: HM43239


Aptose Biosciences Inc.


The following cities have HM43239 clinical trial sites. Please check back often as locations will be updated.


For more information on enrollment in our current clinical trials, please contact us or visit for location information.

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The safety and efficacy of the investigational use of these products have not been determined. There is no guarantee that the investigational use listed will be filed with and/or approved for marketing by a regulatory agency.