[COMPUTERSHARE LOGO] INVESTOR SERVICES Computershare Trust Company of Canada 100 University Avenue Toronto, Ontario M5J 2Y1 Telephone 1-800-663-9097 www.computershare.com CANADA Australia Channel Islands Hong Kong Germany Ireland New Zealand Philippines South Africa United Kingdom USA October 24, 2003 To: Alberta Securities Commission British Columbia Securities Commission Manitoba Securities Commission Office of the Administrator, New Brunswick Securities Commission of Newfoundland and Labrador Nova Scotia Securities Commission Ontario Securities Commission Registrar of Securities, Prince Edward Island Commission des valeurs mobilieres du Quebec Securities Division of the Saskatchewan Financial Services Commission Securities Registry, Government of the Northwest Territories Registrar of Securities, Government of the Yukon Territories Nunavut Legal Registry The Toronto Stock Exchange Dear Sirs: Subject: Lorus Therapeutics Inc. - ------- ----------------------- We confirm that the following English material was sent by pre-paid mail on October 24, 2003, to the registered shareholders of Common Shares of the subject Corporation: 1. Notice of Annual and Special Meeting of Shareholders 2. Management Information Circular 3. Proxy 4. Annual Report including Audited Annual Financial Statements 5. Supplemental Mail List Card 6. Return Envelope We further confirm that copies of the above-mentioned material, together with Supplemental Mail List cards were sent by courier on October 24, 2003 to each intermediary holding shares of the Corporation who responded to the search procedures in compliance with current securities legislation requirements. In compliance with regulations made under the Securities Act, we are providing this confirmation to you in our capacity as agent for the subject Corporation. Yours truly, (Signed) Tanya Balija Assistant Account Manager Stock Transfer Services (416) 263-9661 (416) 981-9800 Fax c.c. Shane Ellis, Lorus Therapeutics Inc.